Published on: Tuesday, June 4, 2024

Mounjaro: Revolutionizing Type 2 Diabetes Treatment and Weight Loss

Eli Lilly has made a significant investment of $5.3 billion to increase the production of Mounjaro, a revolutionary medication for type 2 diabetes and weight loss. This investment aims to meet the high demand for the drug, which has far outpaced supply over the last year.

What is Mounjaro?

Mounjaro, also known as tirzepatide, is an injectable prescription medicine used to improve blood sugar control in adults with type 2 diabetes. It is administered via subcutaneous injections and works by activating GIP and GLP-1 receptors to lower blood sugar and slow food digestion.

How Does Mounjaro Work?

Mounjaro is the first in a new class of treatments for type 2 diabetes. It enhances both first and second phase insulin secretion, reduces glucagon levels, improves insulin sensitivity, decreases food intake, and slows gastric emptying. This results in improved blood sugar control and weight loss.

Side Effects and Cost

Common side effects of Mounjaro include nausea, vomiting, diarrhea, decreased appetite, constipation, upper abdominal discomfort, and abdominal pain. The cost of Mounjaro varies depending on the patient's insurance coverage and location.

Mounjaro vs Ozempic and Wegovy

Mounjaro and Zepbound are manufactured by Eli Lilly, unlike Ozempic and Wegovy, which are manufactured by Novo Nordisk. While all four medications are used to treat type 2 diabetes and promote weight loss, they have different mechanisms of action and side effect profiles.

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Demand for the drugs Mounjaro and Zepbound has far outpaced supply over the last year, forcing Eli Lilly to invest heavily to scale up its manufacturing.

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Mounjaro is the first in a new class for the treatment of type 2 diabetes. Mounjaro is a single peptide that activates GIP and GLP-1 receptors in the body. Mounjaro enhances both first and second phase insulin secretion, reduces glucagon levels, improves insulin sensitivity, decreases food intake, and slows gastric emptying.

Tirzepatide - Wikipedia

Tirzepatide, sold under the brand names Mounjaro and Zepbound, is an antidiabetic medication used for the treatment of type 2 diabetes and for weight loss. Tirzepatide is administered via subcutaneous injections (under the skin).. The most common side effects include nausea, vomiting, diarrhea, decreased appetite, constipation, upper abdominal discomfort, and abdominal pain.

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